mouse BDNF Over-expression AAV

Name
AAV-m-BDNF

Cat No
AAV-253926

Availability
4-5 weeks

This is an AAV expressing Mouse Bdnf.

AAV-253926

AAV-m-BDNF

Ready-to-use AAV expressing Mouse Bdnf (brain derived neurotrophic factor). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

Gene ID

12064

Gene Name (Vector)

brain derived neurotrophic factor

Gene Symbol

Bdnf

ORF Size (aa)

750

ORF Size (bp)

750 bp

RefSeq ID

NM_007540

RefSeq Synonyms

NM_007540, NM_001316310, NM_001285422, NM_001285421, NM_001285420, NM_001285419, NM_001285418, NM_001285417, NM_001285416, NM_001048142, NM_001048141, NM_001048139, BC034862,

Species

mouse

UniGene ID

Mm.1442

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.