mouse AS3MT Over-expression AAV

Name 
AAV-m-AS3MT
Cat No 
AAV-253113
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse As3mt.

AAV-253113
AAV-m-AS3MT

Ready-to-use AAV expressing Mouse As3mt (arsenic (+3 oxidation state) methyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310045H08Rik; Cyt19
Description (Vector)
Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH (By similarity).
Gene ID
57344
Gene Name (Vector)
arsenic (+3 oxidation state) methyltransferase
Gene Symbol
As3mt
ORF Size (aa)
1131
ORF Size (bp)
1131 bp
RefSeq ID
NM_020577
RefSeq Synonyms
NM_020577, BC145663,
Species
mouse
UniGene ID
Mm.28566

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.