mouse SIKE1 Over-expression AAV
This is an AAV expressing Mouse Sike1.
AAV-251370
AAV-m-SIKE1
Ready-to-use AAV expressing Mouse Sike1 (suppressor of IKBKE 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2810005O12Rik; 5730470L24Rik; AI450236; AI839862; Sike; Sikeb
Description (Vector)
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
Gene ID
66641
Gene Name (Vector)
suppressor of IKBKE 1
Gene Symbol
Sike1
ORF Size (aa)
624
RefSeq ID
NM_025679
RefSeq Synonyms
NM_025679, BC004090,
Species
mouse
UniGene ID
Mm.208619
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.