mouse 2610301G19RIK Over-expression AAV

Name 
AAV-m-2610301G19RIK
Cat No 
AAV-250817
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ccar2.

AAV-250817
AAV-m-2610301G19RIK

Ready-to-use AAV expressing Mouse Ccar2 (cell cycle activator and apoptosis regulator 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2610301G19Rik; Dbc1; mKIAA1967
Description (Vector)
Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.
Gene ID
219158
Gene Name (Vector)
cell cycle activator and apoptosis regulator 2
Gene Symbol
Ccar2
ORF Size (aa)
2769
ORF Size (bp)
2769 bp
RefSeq ID
NM_146055
RefSeq Synonyms
NM_146055, BC038346, BC021475,
Species
mouse
UniGene ID
Mm.218284

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.