mouse 1520402A15RIK Over-expression AAV

Name 
AAV-m-1520402A15RIK
Cat No 
AAV-250218
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Lurap1.

AAV-250218
AAV-m-1520402A15RIK

Ready-to-use AAV expressing Mouse Lurap1 (leucine rich adaptor protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1520402A15Rik; Lrp35a
Description (Vector)
Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway. In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, leading to MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin assembly in the lamella (By similarity).
Gene ID
68075
Gene Name (Vector)
leucine rich adaptor protein 1
Gene Symbol
Lurap1
ORF Size (aa)
720
ORF Size (bp)
720 bp
RefSeq ID
NM_026547
RefSeq Synonyms
NM_026547, BC147750, BC147737, BC147059, BC147058,
Species
mouse
UniGene ID
Mm.388915

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.