human SYNE2 Over-expression AAV

Name 
AAV-h-SYNE2
Cat No 
AAV-234260
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SYNE2.

AAV-234260
AAV-h-SYNE2

Ready-to-use AAV expressing Human SYNE2 (spectrin repeat containing nuclear envelope protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EDMD5; KASH domain-containing protein 2; KASH2; Nesp2; nesprin 2; Nesprin-2; NUA; NUANCE; nuclear envelope spectrin repeat protein 2; nucleus and actin connecting element protein; polytrophin; Protein NUANCE; spectrin repeat containing, nuclear envelope 2; synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; SYNE-2; TROPH
Description (eCommerce)
SYNE2/Nesprin 2 is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus [taken from NCBI Entrez Gene (Gene ID: 23224)].
Description (Vector)
SYNE2 is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.
Gene ID
23224
Gene Name (eCommerce)
spectrin repeat containing nuclear envelope protein 2
Gene Name (Vector)
spectrin repeat containing nuclear envelope protein 2
Gene Symbol
SYNE2
HGNC ID
HGNC:17084
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
858
Protein Name (eCommerce)
Nesprin-2
RefSeq ID
NM_015180
RefSeq Synonyms
NM_182914, NM_182913, NM_182910, NM_015180, BC042134,
Research Areas
Cytoskeleton,Immunology,Mitochondrion
Research Areas (Faceted)
cell_biology,immunology
Species
human
Target Sentence
SYNE2/Nesprin 2 is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus [taken from NCBI Entrez Gene (Gene ID: 23224)].
UniProt ID (eCommerce)
Q8WXH0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.