human SPHK2 Over-expression AAV

Name 
AAV-h-SPHK2
Cat No 
AAV-232067
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SPHK2.

AAV-232067
AAV-h-SPHK2

Ready-to-use AAV expressing Human SPHK2 (sphingosine kinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SK 2; SK-2; SPK 2; SPK-2
Description (Vector)
SPHK2 encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
56848
Gene Name (Vector)
sphingosine kinase 2
Gene Symbol
SPHK2
HGNC ID
HGNC:18859
ORF Size (aa)
1857
ORF Size (bp)
1857 bp
RefSeq ID
NM_020126
RefSeq Synonyms
NM_020126, NM_001243876, NM_001204160, NM_001204159, NM_001204158, BC010671, BC006161,
Species
human
UniGene ID
Hs.

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.