human GRHPR Over-expression AAV

Name 
AAV-h-GRHPR
Cat No 
AAV-230771
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GRHPR.

AAV-230771
AAV-h-GRHPR

Ready-to-use AAV expressing Human GRHPR (glyoxylate and hydroxypyruvate reductase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GLXR; GLYD; PH2
Description (Vector)
GRHPR encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.
Gene ID
9380
Gene Name (Vector)
glyoxylate and hydroxypyruvate reductase
Gene Symbol
GRHPR
HGNC ID
HGNC:4570
ORF Size (aa)
987
ORF Size (bp)
987 bp
RefSeq ID
NM_012203
RefSeq Synonyms
NM_012203, BC000605,
Species
human
UniGene ID
Hs.155742

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.