human ARHGAP8 Over-expression AAV

Name 
AAV-h-ARHGAP8
Cat No 
AAV-229574
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ARHGAP8.

AAV-229574
AAV-h-ARHGAP8

Ready-to-use AAV expressing Human ARHGAP8 (Rho GTPase activating protein 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BPGAP1; PP610
Description (Vector)
ARHGAP8 encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Gene ID
23779
Gene Name (Vector)
Rho GTPase activating protein 8
Gene Symbol
ARHGAP8
HGNC ID
HGNC:677
ORF Size (aa)
1302
ORF Size (bp)
1302 bp
RefSeq ID
NM_001017526
RefSeq Synonyms
NM_181335, NM_001198726, NM_001017526, BC048280,
Species
human
UniGene ID
Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.