human ZP2 Over-expression AAV

Name 
AAV-h-ZP2
Cat No 
AAV-228971
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ZP2.

AAV-228971
AAV-h-ZP2

Ready-to-use AAV expressing Human ZP2 (zona pellucida glycoprotein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Zp-2; ZPA
Description (Vector)
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.
Gene ID
7783
Gene Name (Vector)
zona pellucida glycoprotein 2
Gene Symbol
ZP2
HGNC ID
HGNC:13188
ORF Size (aa)
2238
ORF Size (bp)
2238 bp
RefSeq ID
NM_003460
RefSeq Synonyms
NM_003460, NM_001290104, BC096307, BC096306, BC096305, BC096304,
Species
human
UniGene ID
Hs.73982

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.