human ZFYVE20 Over-expression AAV

Name
AAV-h-ZFYVE20

Cat No
AAV-228237

Availability
4-5 weeks

This is an AAV expressing Human RBSN.

AAV-228237

AAV-h-ZFYVE20

Ready-to-use AAV expressing Human RBSN (rabenosyn, RAB effector). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

110 kDa protein; FYVE finger-containing Rab5 effector protein rabenosyn-5; RAB effector RBSN; Rabenosyn-5; ZFYVE20; Zinc finger FYVE domain-containing protein 20; zinc finger, FYVE domain containing 20

Description (eCommerce)

ZFYVE20 belongs to the FYVE zinc finger family of proteins. It interacts with Ras-related proteins that regulate membrane trafficking. A missense mutation in the gene is associated with a defect in the early endocytic pathway [taken from NCBI Entrez Gene (Gene ID: 64145)].

Gene ID

64145

Gene Name (eCommerce)

rabenosyn, RAB effector

Gene Name (Vector)

rabenosyn, RAB effector

Gene Symbol

RBSN

HGNC ID

HGNC:20759

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2355

ORF Size (bp)

2355 bp

Protein Name (eCommerce)

Rabenosyn-5

RefSeq ID

NM_022340

RefSeq Synonyms

NM_022340, NM_001302378, BC106940,

Research Areas

Immunology,Innate Immunity,Signal Transduction,Toll-like Receptor Signaling,Zinc-finger

Research Areas (Faceted)

signal_transduction,immunology,cell_biology

Species

human

Target Sentence

ZFYVE20 belongs to the FYVE zinc finger family of proteins. It interacts with Ras-related proteins that regulate membrane trafficking. A missense mutation in the gene is associated with a defect in the early endocytic pathway [taken from NCBI Entrez Gene (Gene ID: 64145)].

UniGene ID

Hs.706478

UniProt ID (eCommerce)

Q9H1K0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.