human XCR1 Over-expression AAV

Name 
AAV-h-XCR1
Cat No 
AAV-227876
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human XCR1.

AAV-227876
AAV-h-XCR1

Ready-to-use AAV expressing Human XCR1 (X-C motif chemokine receptor 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CCXCR1; GPR5
Description (Vector)
XCR1 is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene ID
2829
Gene Name (Vector)
X-C motif chemokine receptor 1
Gene Symbol
XCR1
HGNC ID
HGNC:1625
ORF Size (aa)
1002
RefSeq ID
NM_005283
RefSeq Synonyms
NM_005283, NM_001024644, BC095533, BC069589, BC069075,
Species
human
UniGene ID
Hs.248116

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.