human WFDC3 Over-expression AAV

Name
AAV-h-WFDC3

Cat No
AAV-227766

Availability
4-5 weeks

This is an AAV expressing Human WFDC3.

AAV-227766

AAV-h-WFDC3

Ready-to-use AAV expressing Human WFDC3 (WAP four-disulfide core domain 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

dJ447F3.3; WAP14

Description (Vector)

WFDC3 encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains four WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. WFDC3 belongs to the telomeric cluster. Alternatively spliced transcript variants have been observed but their full-length nature has not been determined.

Gene ID

140686

Gene Name (Vector)

WAP four-disulfide core domain 3

Gene Symbol

WFDC3

HGNC ID

HGNC:15957

ORF Size (aa)

696

RefSeq ID

NM_080614

RefSeq Synonyms

NM_080614, BC148860, BC146426,

Species

human

UniGene ID

Hs.419126

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.