human TRIP13 Over-expression AAV

Name 
AAV-h-TRIP13
Cat No 
AAV-226499
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TRIP13.

AAV-226499
AAV-h-TRIP13

Ready-to-use AAV expressing Human TRIP13 (thyroid hormone receptor interactor 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
16E1BP; 16E1-BP; HPV16 E1 protein binding protein; HPV16 E1 protein-binding protein; human papillomavirus type 16 E1 protein-binding protein; MVA3; pachytene checkpoint protein 2 homolog; SH3TC1/TRIP13 fusion; Thyroid hormone receptor interactor 13; thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP-13
Description (eCommerce)
TRIP13 (thyroid hormone receptor interactor 13) plays a key role in chromosome recombination and chromosome structure development during meiosis. TRIP13 is required at early steps in meiotic recombination that leads to non-crossovers pathways. It is also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q15645].
Description (Vector)
TRIP13 encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. TRIP13 is one of several that may play a role in early-stage non-small cell lung cancer.
Gene ID
9319
Gene Name (eCommerce)
thyroid hormone receptor interactor 13
Gene Name (Vector)
thyroid hormone receptor interactor 13
Gene Symbol
TRIP13
HGNC ID
HGNC:12307
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1299
ORF Size (bp)
1299 bp
Protein Name (eCommerce)
Pachytene checkpoint protein 2 homolog
RefSeq ID
NM_004237
RefSeq Synonyms
NM_004237, NM_001166260, BC019294, BC000404,
Research Areas
Cell Cycle,DNA Damage/Repair,Immunology,Meiosis,Spermatogenesis,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics,immunology,transcription_translation
Species
human
Target Sentence
TRIP13 (thyroid hormone receptor interactor 13) plays a key role in chromosome recombination and chromosome structure development during meiosis. TRIP13 is required at early steps in meiotic recombination that leads to non-crossovers pathways. It is also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q15645].
UniGene ID
Hs.436187
UniProt ID (eCommerce)
Q15645

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.