human TPM3 Over-expression AAV
This is an AAV expressing Human TPM3.
AAV-226271
AAV-h-TPM3
Ready-to-use AAV expressing Human TPM3 (tropomyosin 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAPM1; CFTD; HEL-189; HEL-S-82p; hscp30; NEM1; OK/SW-cl.5; TM-5; TM3; TM30; TM30nm; TM5; TPMsk3; TRK
Description (Vector)
TPM3 encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
7170
Gene Name (Vector)
tropomyosin 3
Gene Symbol
TPM3
HGNC ID
HGNC:12012
ORF Size (aa)
477
RefSeq ID
NM_152263
RefSeq Synonyms
NM_153649, NM_152263, NM_001278191, NM_001278190, NM_001278189, NM_001278188, NM_001043353, NM_001043352, NM_001043351, BC072428, BC062740, BC015403, BC008425, BC008407, BC000771,
Species
human
UniGene ID
Hs.654421
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.