human TNPO3 Over-expression AAV

Name 
AAV-h-TNPO3
Cat No 
AAV-226153
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TNPO3.

AAV-226153
AAV-h-TNPO3

Ready-to-use AAV expressing Human TNPO3 (transportin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IPO12; LGMD1F; MTR10A; TRN-SR; TRN-SR2; TRNSR
Description (Vector)
TNPO3 is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.
Gene ID
23534
Gene Name (Vector)
transportin 3
Gene Symbol
TNPO3
HGNC ID
HGNC:17103
ORF Size (aa)
2772
ORF Size (bp)
2772 bp
RefSeq ID
NM_012470
RefSeq Synonyms
NM_012470, NM_001191028, BC172512, BC156517,
Species
human
UniGene ID
Hs.193613

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.