human GLB1 Over-expression AAV

Name 
AAV-h-GLB1
Cat No 
AAV-226003
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GLB1.

AAV-226003
AAV-h-GLB1

Ready-to-use AAV expressing Human GLB1 (galactosidase beta 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EBP; ELNR1; MPS4B
Description (Vector)
GLB1 encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
2720
Gene Name (Vector)
galactosidase beta 1
Gene Symbol
GLB1
HGNC ID
HGNC:4298
ORF Size (aa)
2034
ORF Size (bp)
2034 bp
RefSeq ID
NM_000404
RefSeq Synonyms
NM_001317040, NM_001135602, NM_001079811, NM_000404, BC007493,
Species
human
UniGene ID
Hs.443031

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.