human TIMM8B Over-expression AAV

Name 
AAV-h-TIMM8B
Cat No 
AAV-225525
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TIMM8B.

AAV-225525
AAV-h-TIMM8B

Ready-to-use AAV expressing Human TIMM8B (translocase of inner mitochondrial membrane 8 homolog B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DDP2; TIM8B
Description (Vector)
TIMM8B encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. TIMM8B is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. TIMM8B is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma.
Gene ID
26521
Gene Name (Vector)
translocase of inner mitochondrial membrane 8 homolog B
Gene Symbol
TIMM8B
HGNC ID
HGNC:11818
ORF Size (aa)
156
RefSeq ID
NM_012459
RefSeq Synonyms
NM_012459, BC106067, BC105986, BC000711,
Species
human
UniGene ID
Hs.279915

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.