human TGIF2 Over-expression AAV

Name 
AAV-h-TGIF2
Cat No 
AAV-225395
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TGIF2.

AAV-225395
AAV-h-TGIF2

Ready-to-use AAV expressing Human TGIF2 (TGFB induced factor homeobox 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
TGIF2 is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene.
Gene ID
60436
Gene Name (Vector)
TGFB induced factor homeobox 2
Gene Symbol
TGIF2
HGNC ID
HGNC:15764
ORF Size (aa)
714
RefSeq ID
NM_021809
RefSeq Synonyms
NM_021809, NM_001199515, NM_001199514, NM_001199513, BC012816, BC006549,
Species
human
UniGene ID
Hs.632264

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.