human TCN2 Over-expression AAV

Name 
AAV-h-TCN2
Cat No 
AAV-225235
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TCN2.

AAV-225235
AAV-h-TCN2

Ready-to-use AAV expressing Human TCN2 (transcobalamin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D22S676; D22S750; II; TC; TC II; TC-2; TC2; TCII
Description (Vector)
TCN2 encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.
Gene ID
6948
Gene Name (Vector)
transcobalamin 2
Gene Symbol
TCN2
HGNC ID
HGNC:11653
ORF Size (aa)
1284
ORF Size (bp)
1284 bp
RefSeq ID
NM_000355
RefSeq Synonyms
NM_001184726, NM_000355, BC011239, BC001176,
Species
human
UniGene ID
Hs.417948

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.