human SYT14 Over-expression AAV

Name 
AAV-h-SYT14
Cat No 
AAV-224845
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SYT14.

AAV-224845
AAV-h-SYT14

Ready-to-use AAV expressing Human SYT14 (synaptotagmin 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SCAR11; sytXIV
Description (Vector)
SYT14 is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmin. Mutations in this gene are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11), and a t(1;3) translocation of this gene has been associated with neurodevelopmental abnormalities. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4.
Gene ID
255928
Gene Name (Vector)
synaptotagmin 14
Gene Symbol
SYT14
HGNC ID
HGNC:23143
ORF Size (aa)
1809
ORF Size (bp)
1809 bp
RefSeq ID
NM_153262
RefSeq Synonyms
NM_153262, NM_001256006, NM_001146264, NM_001146262, NM_001146261, BC130323,
Species
human
UniGene ID
Hs.658866

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.