human SNAI2 Over-expression AAV

Name 
AAV-h-SNAI2
Cat No 
AAV-223804
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SNAI2.

AAV-223804
AAV-h-SNAI2

Ready-to-use AAV expressing Human SNAI2 (snail family transcriptional repressor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
neural crest transcription factor SLUG; protein snail homolog 2; SLUG; slug (chicken homolog), zinc finger protein; SLUGH; SLUGH1; snail family zinc finger 2; snail homolog 2; SNAIL2; WS2D; zinc finger protein SNAI2
Description (eCommerce)
Slug is a member of the Snail family of C2H2-type zinc finger transcription factors. It acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. Slug is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. [taken from NCBI Entrez Gene (Gene ID: 6591)].
Description (Vector)
SNAI2 encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
Gene ID
6591
Gene Name (eCommerce)
snail family transcriptional repressor 2
Gene Name (Vector)
snail family transcriptional repressor 2
Gene Symbol
SNAI2
HGNC ID
HGNC:11094
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
807
Protein Name (eCommerce)
Zinc finger protein SNAI2
RefSeq ID
NM_003068
RefSeq Synonyms
NM_003068, BC015895, BC014890,
Research Areas
Apoptosis,Breast Cancer,Cancer,DNA Damage/Repair,Hippo Signaling,Histone Modification,Neurobiology,Neurodevelopment,Notch Signaling,SCF-KIT Signaling,Signal Transduction,Transcription Factor/Regulator,Wnt Signaling,Zinc-finger
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,genetics,transcription_translation,signal_transduction,developmental_biology,genetics,neurobiology,developmental_biology,developmental_biology,signal_transduction,stem_cell_biology,genetics,transcription_translation,signal_transduction,developmental_biology,cell_biology
Species
human
Target Sentence
Slug is a member of the Snail family of C2H2-type zinc finger transcription factors. It acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. Slug is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. [taken from NCBI Entrez Gene (Gene ID: 6591)].
UniGene ID
Hs.360174
UniProt ID (eCommerce)
O43623

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.