human SLCO1B1 Over-expression AAV

Name 
AAV-h-SLCO1B1
Cat No 
AAV-223627
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SLCO1B1.

AAV-223627
AAV-h-SLCO1B1

Ready-to-use AAV expressing Human SLCO1B1 (solute carrier organic anion transporter family member 1B1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2; OATPC; SLC21A6
Description (Vector)
SLCO1B1 encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.
Gene ID
10599
Gene Name (Vector)
solute carrier organic anion transporter family member 1B1
Gene Symbol
SLCO1B1
HGNC ID
HGNC:10959
ORF Size (aa)
2076
ORF Size (bp)
2076 bp
RefSeq ID
NM_006446
RefSeq Synonyms
NM_006446, BC114376,
Species
human
UniGene ID
Hs.449738

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.