human SIAH1 Over-expression AAV

Name 
AAV-h-SIAH1
Cat No 
AAV-222979
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SIAH1.

AAV-222979
AAV-h-SIAH1

Ready-to-use AAV expressing Human SIAH1 (siah E3 ubiquitin protein ligase 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SIAH1A
Description (Vector)
SIAH1 encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Gene ID
6477
Gene Name (Vector)
siah E3 ubiquitin protein ligase 1
Gene Symbol
SIAH1
HGNC ID
HGNC:10857
ORF Size (aa)
942
RefSeq ID
NM_003031
RefSeq Synonyms
NM_003031, NM_001006610, BC044920, BC042550, BC035562,
Species
human
UniGene ID
Hs.295923

Recently Viewed Products

AAV-h-HHLA2

Cat No: AAV-211010

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.