human SERPINA3 Over-expression AAV

Name 
AAV-h-SERPINA3
Cat No 
AAV-222672
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SERPINA3.

AAV-222672
AAV-h-SERPINA3

Ready-to-use AAV expressing Human SERPINA3 (serpin family A member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AACT; ACT; GIG24; GIG25
Description (Vector)
SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Gene ID
12
Gene Name (Vector)
serpin family A member 3
Gene Symbol
SERPINA3
HGNC ID
HGNC:16
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
RefSeq ID
NM_001085
RefSeq Synonyms
NM_001085, BC034554, BC010530, BC003559,
Species
human
UniGene ID
Hs.710488

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.