human SERAC1 Over-expression AAV

Name
AAV-h-SERAC1

Cat No
AAV-222626

Availability
4-5 weeks

This is an AAV expressing Human SERAC1.

AAV-222626

AAV-h-SERAC1

Ready-to-use AAV expressing Human SERAC1 (serine active site containing 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

SERAC1 is a phosphatidylglycerol remodeling protein found at the interface of mitochondria and endoplasmic reticula, where it mediates phospholipid exchange. The encoded protein plays a major role in mitochondrial function and intracellular cholesterol trafficking. Defects in this gene are a cause of 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (MEGDEL). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.

Gene ID

84947

Gene Name (Vector)

serine active site containing 1

Gene Symbol

SERAC1

HGNC ID

HGNC:21061

ORF Size (aa)

1965

ORF Size (bp)

1965 bp

RefSeq ID

NM_032861

RefSeq Synonyms

NM_032861, BC001705,

Species

human

UniGene ID

Hs.154706

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.