human SEPW1 Over-expression AAV

Name 
AAV-h-SEPW1
Cat No 
AAV-222621
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SELENOW.

AAV-222621
AAV-h-SEPW1

Ready-to-use AAV expressing Human SELENOW (selenoprotein W). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
selW; SEPW1
Description (Vector)
SEPW1 encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein shows highest expression in skeletal muscle and heart, and may be involved in oxidation-reduction reactions. A retroprocessed pseudogene, SEPW1P, has been identified and mapped to chromosome 1p35-34.
Gene ID
6415
Gene Name (Vector)
selenoprotein W
Gene Symbol
SELENOW
HGNC ID
HGNC:10752
ORF Size (aa)
264
RefSeq ID
NM_003009
RefSeq Synonyms
NM_003009, BC047893, BC039597, BC032546, BC000581,
Species
human
UniGene ID
Hs.631549

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.