human SEPN1 Over-expression AAV
This is an AAV expressing Human SEPN1.
AAV-222587
AAV-h-SEPN1
Ready-to-use AAV expressing Human SEPN1 (selenoprotein N, 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FLJ24021; MDRS1; RSMD1; RSS; SELN;
Description (Vector)
SEPN1 encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
57190
Gene Name (Vector)
selenoprotein N, 1
Gene Symbol
SEPN1
ORF Size (aa)
1770
ORF Size (bp)
1770 bp
RefSeq ID
NM_020451
RefSeq Synonyms
NM_206926, NM_020451, BC156071,
Species
human
UniGene ID
Hs.568578
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.