human SENP2 Over-expression AAV

Name 
AAV-h-SENP2
Cat No 
AAV-222574
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SENP2.

AAV-222574
AAV-h-SENP2

Ready-to-use AAV expressing Human SENP2 (SUMO1/sentrin/SMT3 specific peptidase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AXAM2; sentrin (SUMO1) specific peptidase 2; sentrin/SUMO-specific protease SENP2; sentrin-specific protease 2; SMT3IP2; SMT3-specific isopeptidase 2; SUMO1/sentrin/SMT3 specific peptidase 2; SUMO1/sentrin/SMT3 specific protease 2
Description (eCommerce)
Sentrin-specific protease 2 catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP2 may play a role in down-regulating CTNNB1 levels and thereby modulate the Wnt pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9HC62].
Description (Vector)
SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.(supplied by OMIM, Apr 2004)
Gene ID
59343
Gene Name (eCommerce)
SUMO specific peptidase 2
Gene Name (Vector)
SUMO1/sentrin/SMT3 specific peptidase 2
Gene Symbol
SENP2
HGNC ID
HGNC:23116
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1770
ORF Size (bp)
1770 bp
Protein Name (eCommerce)
Sentrin-specific protease 2
RefSeq ID
NM_021627
RefSeq Synonyms
NM_021627, BC040609,
Research Areas
mRNA transport,RNA Transport,Signal Transduction,Wnt Signaling
Research Areas (Faceted)
cell_biology,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
Sentrin-specific protease 2 catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP2 may play a role in down-regulating CTNNB1 levels and thereby modulate the Wnt pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9HC62].
UniGene ID
Hs.401388
UniProt ID (eCommerce)
Q9HC62

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.