human SDPR Over-expression AAV

Name 
AAV-h-SDPR
Cat No 
AAV-222450
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SDPR.

AAV-222450
AAV-h-SDPR

Ready-to-use AAV expressing Human SDPR (serum deprivation response). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cavin-2; CAVIN2; PS-p68; SDR
Description (Vector)
SDPR encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.
Gene ID
8436
Gene Name (Vector)
serum deprivation response
Gene Symbol
SDPR
HGNC ID
HGNC:10690
ORF Size (aa)
1278
ORF Size (bp)
1278 bp
RefSeq ID
NM_004657
RefSeq Synonyms
NM_004657, BC016475,
Species
human
UniGene ID
Hs.26530

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.