human RRN3 Over-expression AAV

Name 
AAV-h-RRN3
Cat No 
AAV-222008
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RRN3.

AAV-222008
AAV-h-RRN3

Ready-to-use AAV expressing Human RRN3 (RRN3 homolog, RNA polymerase I transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A-270G1.2; RNA polymerase I-specific transcription initiation factor RRN3; RRN3 RNA polymerase I transcription factor homolog; TIFIA; TIF-IA; transcription initiation factor IA; transcription initiation factor TIF-IA
Description (eCommerce)
Transcription initiation factor IA (TIF-IA) is encoded by the RRN3 gene which was identified and cloned due to its homology with the yeast Rrn3p gene. TIF-IA has been shown to recruit initiation-competent RNA Polymerase I to rRNA promoters.
Gene ID
54700
Gene Name (eCommerce)
RRN3 homolog, RNA polymerase I transcription factor
Gene Name (Vector)
RRN3 homolog, RNA polymerase I transcription factor
Gene Symbol
RRN3
HGNC ID
HGNC:30346
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1956
ORF Size (bp)
1956 bp
Protein Name (eCommerce)
RNA polymerase I-specific transcription initiation factor RRN3
RefSeq ID
NM_018427
RefSeq Synonyms
NM_018427, NM_001301064, BC132690, BC132688,
Research Areas
Apoptosis,Gene Expression,mTOR Signaling,RNA Binding,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
Transcription initiation factor IA (TIF-IA) is encoded by the RRN3 gene which was identified and cloned due to its homology with the yeast Rrn3p gene. TIF-IA has been shown to recruit initiation-competent RNA Polymerase I to rRNA promoters.
UniGene ID
Hs.460078
UniProt ID (eCommerce)
Q9NYV6

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.