human RPS19BP1 Over-expression AAV

Name 
AAV-h-RPS19BP1
Cat No 
AAV-221856
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RPS19BP1.

AAV-221856
AAV-h-RPS19BP1

Ready-to-use AAV expressing Human RPS19BP1 (ribosomal protein S19 binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
40S ribosomal protein S19-binding protein 1; active regulator of SIRT1; AROS; homolog of mouse S19 binding protein; RPS19-binding protein 1; S19BP
Description (eCommerce)
The protein active regulator of SIRT1, also known as Ribosomal Protein S19 Binding Protein 1, is a direct regulator of SIRT1. By enhancing SIRT1-mediated deacetylation of p53/TP53 this protein participates in the inhibition of p53/TP53-mediated transcriptional activity. Active regulator of SIRT1 is encoded for by the gene RPS19BP1, also known as AROS or S19BP [taken from UniProtKB (Entry: Q86WX3)].
Gene ID
91582
Gene Name (eCommerce)
ribosomal protein S19 binding protein 1
Gene Name (Vector)
ribosomal protein S19 binding protein 1
Gene Symbol
RPS19BP1
HGNC ID
HGNC:28749
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
411
ORF Size (bp)
411 bp
Protein Name (eCommerce)
Active regulator of SIRT1
RefSeq ID
NM_194326
RefSeq Synonyms
NM_194326, BC047711, BC037573,
Research Areas
Cell Biology
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
The protein active regulator of SIRT1, also known as Ribosomal Protein S19 Binding Protein 1, is a direct regulator of SIRT1. By enhancing SIRT1-mediated deacetylation of p53/TP53 this protein participates in the inhibition of p53/TP53-mediated transcriptional activity. Active regulator of SIRT1 is encoded for by the gene RPS19BP1, also known as AROS or S19BP [taken from UniProtKB (Entry: Q86WX3)].
UniGene ID
Hs.526933
UniProt ID (eCommerce)
Q86WX3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.