human RNF4 Over-expression AAV

Name 
AAV-h-RNF4
Cat No 
AAV-221430
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RNF4.

AAV-221430
AAV-h-RNF4

Ready-to-use AAV expressing Human RNF4 (ring finger protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RES4-26; SLX5; SNURF
Description (Vector)
RNF4 contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.
Gene ID
6047
Gene Name (Vector)
ring finger protein 4
Gene Symbol
RNF4
HGNC ID
HGNC:10067
ORF Size (aa)
573
RefSeq ID
NM_002938
RefSeq Synonyms
NM_002938, NM_001185010, NM_001185009, BC031935,
Species
human
UniGene ID
Hs.66394

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.