human RNF34 Over-expression AAV

Name 
AAV-h-RNF34
Cat No 
AAV-221427
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RNF34.

AAV-221427
AAV-h-RNF34

Ready-to-use AAV expressing Human RNF34 (ring finger protein 34). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CARP-1; CARP1; hRFI; RFI; RIF; RIFF
Description (Vector)
RNF34 contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
80196
Gene Name (Vector)
ring finger protein 34
Gene Symbol
RNF34
HGNC ID
HGNC:17297
ORF Size (aa)
1119
ORF Size (bp)
1119 bp
RefSeq ID
NM_025126
RefSeq Synonyms
NM_194271, NM_025126, NM_001256858, BC007826,
Species
human
UniGene ID
Hs.292804

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.