human RHOC Over-expression AAV

Name 
AAV-h-RHOC
Cat No 
AAV-221179
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RHOC.

AAV-221179
AAV-h-RHOC

Ready-to-use AAV expressing Human RHOC (ras homolog family member C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARH9; ARHC; H9; RHOH9
Description (Vector)
RHOC encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
389
Gene Name (Vector)
ras homolog family member C
Gene Symbol
RHOC
HGNC ID
HGNC:669
ORF Size (aa)
582
RefSeq ID
NM_175744
RefSeq Synonyms
NM_175744, NM_001042679, NM_001042678, BC052808, BC009177, BC007245,
Species
human
UniGene ID
Hs.658289

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.