human RGS17 Over-expression AAV

Name 
AAV-h-RGS17
Cat No 
AAV-221116
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RGS17.

AAV-221116
AAV-h-RGS17

Ready-to-use AAV expressing Human RGS17 (regulator of G-protein signaling 17). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hRGS17; RGS-17; RGSZ2
Description (Vector)
RGS17 encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Gene ID
26575
Gene Name (Vector)
regulator of G-protein signaling 17
Gene Symbol
RGS17
HGNC ID
HGNC:14088
ORF Size (aa)
633
RefSeq ID
NM_012419
RefSeq Synonyms
NM_012419, BC013117,
Species
human
UniGene ID
Hs.166313

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.