human RAX2 Over-expression AAV

Name 
AAV-h-RAX2
Cat No 
AAV-220816
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RAX2.

AAV-220816
AAV-h-RAX2

Ready-to-use AAV expressing Human RAX2 (retina and anterior neural fold homeobox 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARMD6; CORD11; QRX; RAXL1
Description (Vector)
RAX2 encodes a homeodomain-containing protein that plays a role in eye development. Mutation of this gene causes age-related macular degeneration type 6, an eye disorder resulting in accumulations of protein and lipid beneath the retinal pigment epithelium and within the Bruch's membrane. Defects in this gene can also cause cone-rod dystrophy type 11, a disease characterized by the initial degeneration of cone photoreceptor cells and resulting in loss of color vision and visual acuity, followed by the degeneration of rod photoreceptor cells, which progresses to night blindness and the loss of peripheral vision.
Gene ID
84839
Gene Name (Vector)
retina and anterior neural fold homeobox 2
Gene Symbol
RAX2
HGNC ID
HGNC:18286
ORF Size (aa)
555
RefSeq ID
NM_032753
RefSeq Synonyms
NM_032753, NM_001319074, BC032512, BC018709, BC007284,
Species
human
UniGene ID
Hs.532691

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.