human RABGGTB Over-expression AAV

Name 
AAV-h-RABGGTB
Cat No 
AAV-220610
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RABGGTB.

AAV-220610
AAV-h-RABGGTB

Ready-to-use AAV expressing Human RABGGTB (Rab geranylgeranyltransferase beta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Geranylgeranyl transferase type II subunit beta; geranylgeranyl transferase type-2 subunit beta; GGTase-II-beta; GGTB; Rab geranylgeranyltransferase beta subunit; Rab geranylgeranyltransferase subunit beta; Rab geranyl-geranyltransferase subunit beta; rab GG transferase beta; rab GGTase beta; type II protein geranyl-geranyltransferase subunit beta
Description (eCommerce)
Rab geranyl-geranyltransferase subunit beta (RABGGTB) catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P53611].
Gene ID
5876
Gene Name (eCommerce)
Rab geranylgeranyltransferase subunit beta
Gene Name (Vector)
Rab geranylgeranyltransferase beta subunit
Gene Symbol
RABGGTB
HGNC ID
HGNC:9796
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
996
ORF Size (bp)
996 bp
Protein Name (eCommerce)
Geranylgeranyl transferase type-2 subunit beta
RefSeq ID
NM_004582
RefSeq Synonyms
NM_004582, BC020790,
Research Areas
Metabolism/Metabolic Process,Neurobiology
Research Areas (Faceted)
cell_biology,metabolism,neurobiology
Species
human
Target Sentence
Rab geranyl-geranyltransferase subunit beta (RABGGTB) catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P53611].
UniGene ID
Hs.78948
UniProt ID (eCommerce)
P53611

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.