human PTPN22 Over-expression AAV

Name 
AAV-h-PTPN22
Cat No 
AAV-220320
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PTPN22.

AAV-220320
AAV-h-PTPN22

Ready-to-use AAV expressing Human PTPN22 (protein tyrosine phosphatase, non-receptor type 22). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LYP; LYP1; LYP2; PEP; PTPN8
Description (Vector)
PTPN22 encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene ID
26191
Gene Name (Vector)
protein tyrosine phosphatase, non-receptor type 22
Gene Symbol
PTPN22
HGNC ID
HGNC:9652
ORF Size (aa)
2259
ORF Size (bp)
2259 bp
RefSeq ID
NM_012411
RefSeq Synonyms
NM_015967, NM_012411, NM_001308297, NM_001193431, BC071670, BC017785,
Species
human
UniGene ID
Hs.535276

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.