human PTP4A1 Over-expression AAV

Name 
AAV-h-PTP4A1
Cat No 
AAV-220296
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PTP4A1.

AAV-220296
AAV-h-PTP4A1

Ready-to-use AAV expressing Human PTP4A1 (protein tyrosine phosphatase type IVA, member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HH72; PRL-1; PRL1; PTP(CAAX1); PTPCAAX1
Description (Vector)
PTP4A1 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.
Gene ID
7803
Gene Name (Vector)
protein tyrosine phosphatase type IVA, member 1
Gene Symbol
PTP4A1
HGNC ID
HGNC:9634
ORF Size (aa)
522
RefSeq ID
NM_003463
RefSeq Synonyms
NM_003463, BC045571, BC023975,
Species
human
UniGene ID
Hs.227777

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.