human PSMB7 Over-expression AAV

epididymis secretory sperm binding protein; macropain chain ; Zmulticatalytic endopeptidase complex chain ; Zproteasome (prosome, macropain) subunit, beta type, 7; proteasome catalytic subunit 2; proteasome subunit alpha; proteasome subunit beta type-7; proteasome subunit ; Zprotein serine kinase c17; Z

PSMB7 [proteasome (prosome, macropain) subunit, beta type,7] is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit [taken from NCBI Entrez Gene (Gene ID: 5695)].

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14.

5695

proteasome subunit beta 7

proteasome subunit beta 7

PSMB7

HGNC:9544

9606.0

834

Proteasome subunit beta type-7

NM_002799

NM_002799, BC000509,

Antigen Processing and Presentation,Apoptosis,B-cell Receptor Signaling,Cell Cycle,Cell Division,Complexome,DNA Damage/Repair,Gene Expression,Hedgehog Signaling,Host-Virus Interactions,Immunology,Interleukin Signaling,JAK-STAT Signaling,Metabolism/Metabolic Process,NF-kB Signaling,Notch Signaling,Proteasome,RNA Processing,Signal Transduction,T-cell Receptor Signaling,TGF-beta Signaling,TNF Signaling,Toll-like Receptor Signaling,Ubiquitination,Wnt Signaling

signal_transduction,immunology,cell_biology,signal_transduction,immunology,cell_biology,cell_cycle,genetics,transcription_translation,signal_transduction,developmental_biology,infectious_disease,immunology,signal_transduction,metabolism,signal_transduction,immunology,developmental_biology,cell_biology,genetics,transcription_translation,signal_transduction,immunology,genetics,developmental_biology

human

PSMB7 [proteasome (prosome, macropain) subunit, beta type,7] is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit [taken from NCBI Entrez Gene (Gene ID: 5695)].

Hs.213470

Q99436