human PSIP1 Over-expression AAV

Name 
AAV-h-PSIP1
Cat No 
AAV-220082
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PSIP1.

AAV-220082
AAV-h-PSIP1

Ready-to-use AAV expressing Human PSIP1 (PC4 and SFRS1 interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CLL-associated antigen KW-7; dense fine speckles 70 kDa protein; DFS 70; DFS70; LEDGF; lens epithelium-derived growth factor; p52; p75; PAIP; PC4 and SFRS1-interacting protein; PSIP2; transcriptional coactivator p52/p75; Transcriptional coactivator p75/p52
Description (eCommerce)
LEDGF/p75 has been identified as a transcriptional coactivator involved in lens epithelial cell gene regulation and in neuroepithelial stem cell differentiation and neurogenesis. LEDGF has also been shown to function as a cofactor for lentivirus and HIV integration.
Gene ID
11168
Gene Name (eCommerce)
PC4 and SFRS1 interacting protein 1
Gene Name (Vector)
PC4 and SFRS1 interacting protein 1
Gene Symbol
PSIP1
HGNC ID
HGNC:9527
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
975
ORF Size (bp)
975 bp
Protein Name (eCommerce)
PC4 and SFRS1-interacting protein
RefSeq ID
NM_021144
RefSeq Synonyms
NM_033222, NM_021144, NM_001317900, NM_001317898, NM_001128217, BC064135, BC044568,
Research Areas
Host-Virus Interactions,Neurobiology,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,infectious_disease,neurobiology,transcription_translation
Species
human
Target Sentence
LEDGF/p75 has been identified as a transcriptional coactivator involved in lens epithelial cell gene regulation and in neuroepithelial stem cell differentiation and neurogenesis. LEDGF has also been shown to function as a cofactor for lentivirus and HIV integration.
UniGene ID
Hs.658434
UniProt ID (eCommerce)
O75475

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.