human PRPF4 Over-expression AAV

Name
AAV-h-PRPF4

Cat No
AAV-219959

Availability
4-5 weeks

This is an AAV expressing Human PRPF4.

AAV-219959

AAV-h-PRPF4

Ready-to-use AAV expressing Human PRPF4 (pre-mRNA processing factor 4). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HPRP4; HPRP4P; PRP4; Prp4p; RP70; SNRNP60

Description (Vector)

PRPF4 is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

9128

Gene Name (Vector)

pre-mRNA processing factor 4

Gene Symbol

PRPF4

HGNC ID

HGNC:17349

ORF Size (aa)

1569

ORF Size (bp)

1569 bp

RefSeq ID

NM_004697

RefSeq Synonyms

NM_004697, NM_001322267, NM_001322266, NM_001244926, BC007424, BC001588,

Species

human

UniGene ID

Hs.530284

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.