human PPT1 Over-expression AAV
This is an AAV expressing Human PPT1.
AAV-219694
AAV-h-PPT1
Ready-to-use AAV expressing Human PPT1 (palmitoyl-protein thioesterase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CLN1; INCL; PPT
Description (Vector)
PPT1 is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
5538
Gene Name (Vector)
palmitoyl-protein thioesterase 1
Gene Symbol
PPT1
HGNC ID
HGNC:9325
ORF Size (aa)
921
RefSeq ID
NM_000310
RefSeq Synonyms
NM_001142604, NM_000310, BC008426,
Species
human
UniGene ID
Hs.3873
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.