human PPP1R1B Over-expression AAV

Name 
AAV-h-PPP1R1B
Cat No 
AAV-219628
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PPP1R1B.

AAV-219628
AAV-h-PPP1R1B

Ready-to-use AAV expressing Human PPP1R1B (protein phosphatase 1 regulatory inhibitor subunit 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DARPP-32; DARPP32
Description (Vector)
PPP1R1B encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
84152
Gene Name (Vector)
protein phosphatase 1 regulatory inhibitor subunit 1B
Gene Symbol
PPP1R1B
HGNC ID
HGNC:9287
ORF Size (aa)
507
RefSeq ID
NM_032192
RefSeq Synonyms
NM_181505, NM_032192, NM_001242464, BC001519,
Species
human
UniGene ID
Hs.286192

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.