human PPAP2B Over-expression AAV

Name 
AAV-h-PPAP2B
Cat No 
AAV-219500
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PLPP3.

AAV-219500
AAV-h-PPAP2B

Ready-to-use AAV expressing Human PLPP3 (phospholipid phosphatase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Dri42; LPP3; PAP2B; PPAP2B; VCIP
Description (Vector)
PPAP2B is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells.
Gene ID
8613
Gene Name (Vector)
phospholipid phosphatase 3
Gene Symbol
PLPP3
HGNC ID
HGNC:9229
ORF Size (aa)
936
RefSeq ID
NM_003713
RefSeq Synonyms
NM_003713, BC009196,
Species
human
UniGene ID
Hs.715848

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.