human PPAP2A Over-expression AAV

Name 
AAV-h-PPAP2A
Cat No 
AAV-219497
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PLPP1.

AAV-219497
AAV-h-PPAP2A

Ready-to-use AAV expressing Human PLPP1 (phospholipid phosphatase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LLP1a; LPP1; PAP-2a; PAP2; PPAP2A
Description (Vector)
PPAP2A is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene ID
8611
Gene Name (Vector)
phospholipid phosphatase 1
Gene Symbol
PLPP1
HGNC ID
HGNC:9228
ORF Size (aa)
855
RefSeq ID
NM_003711
RefSeq Synonyms
NM_176895, NM_003711, BC143281, BC117133, BC039847,
Species
human
UniGene ID
Hs.696231

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.