human POU6F2 Over-expression AAV

Name 
AAV-h-POU6F2
Cat No 
AAV-219490
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human POU6F2.

AAV-219490
AAV-h-POU6F2

Ready-to-use AAV expressing Human POU6F2 (POU class 6 homeobox 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RPF-1; WT5; WTSL
Description (Vector)
POU6F2 encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. POU6F2 is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
11281
Gene Name (Vector)
POU class 6 homeobox 2
Gene Symbol
POU6F2
HGNC ID
HGNC:21694
ORF Size (aa)
2049
ORF Size (bp)
2049 bp
RefSeq ID
NM_007252
RefSeq Synonyms
NM_007252, NM_001166018, BC152915,
Species
human
UniGene ID
Hs.137106

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.