human PON1 Over-expression AAV

Name 
AAV-h-PON1
Cat No 
AAV-219442
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PON1.

AAV-219442
AAV-h-PON1

Ready-to-use AAV expressing Human PON1 (paraoxonase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ESA; MVCD5; PON
Description (Vector)
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
Gene ID
5444
Gene Name (Vector)
paraoxonase 1
Gene Symbol
PON1
HGNC ID
HGNC:9204
ORF Size (aa)
1068
RefSeq ID
NM_000446
RefSeq Synonyms
NM_000446, BC074719,
Species
human
UniGene ID
Hs.370995

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.