human POLR1E Over-expression AAV

Name 
AAV-h-POLR1E
Cat No 
AAV-219384
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human POLR1E.

AAV-219384
AAV-h-POLR1E

Ready-to-use AAV expressing Human POLR1E (RNA polymerase I subunit E). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DNA-directed RNA polymerase I subunit E; DNA-directed RNA polymerase I subunit RPA49; PAF53; polymerase (RNA) I associated factor 1; polymerase (RNA) I polypeptide E, 53kDa; polymerase (RNA) I subunit E; PRAF1; RNA polymerase I subunit A49; RNA polymerase I-associated factor 1; RNA polymerase I-associated factor 53
Description (eCommerce)
POLR1E is a DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is a component of RNA polymerase I which synthesizes ribosomal RNA precursors and appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9GZS1].
Gene ID
64425
Gene Name (eCommerce)
RNA polymerase I subunit E
Gene Name (Vector)
RNA polymerase I subunit E
Gene Symbol
POLR1E
HGNC ID
HGNC:17631
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1260
ORF Size (bp)
1260 bp
Protein Name (eCommerce)
DNA-directed RNA polymerase I subunit RPA49
RefSeq ID
NM_022490
RefSeq Synonyms
NM_022490, NM_001282766, BC014331, BC001337,
Research Areas
Epigenetic Regulation of Gene Expression,Signal Transduction,TNF Signaling
Research Areas (Faceted)
cell_biology,genetics,signal_transduction
Species
human
Target Sentence
POLR1E is a DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is a component of RNA polymerase I which synthesizes ribosomal RNA precursors and appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9GZS1].
UniGene ID
Hs.591087
UniProt ID (eCommerce)
Q9GZS1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.